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Writer's pictureSally Harvey

Study highlights the efficacy of Platelet-Rich Plasma (PRP) for skin rejuvenation



A recent comprehensive review published on PubMed has revealed significant advancements in the use of Platelet-Rich Plasma (PRP) for skin rejuvenation. The study, led by Dr Lam Kar Wai Phoebe and a team of researchers from various medical institutions, emphasises PRP's growing recognition as a safe and effective treatment for improving skin quality and combating signs of aging.


The study aimed to assess the efficacy of PRP treatments specifically for skin rejuvenation. The research team conducted a thorough review of existing studies, using keywords such as "platelet-rich plasma," "rejuvenation," "skin aging," and "wrinkles" across databases like Ovid, PubMed, and MEDLINE. Eleven studies, involving a total of 382 participants, met the rigorous criteria for analysis.


PRP treatment demonstrated significant improvements in various skin parameters after one to three sessions. Notable enhancements included reduced pore size, improved skin texture, and a decrease in wrinkles and pigmented spots. PRP treatments also boosted collagen density, hyaluronic acid levels, and provided protection against ultraviolet (UV) damage.

One of the standout findings was the synergistic effect observed when PRP was combined with hyaluronic acid, particularly in enhancing skin elasticity and firmness in patients aged 50 and above.


The study highlighted the superiority of combining both physical and biometric data for a more comprehensive assessment of skin quality. This dual approach provided a more accurate evaluation of subtle changes in skin structure, beyond what physical observations alone could detect.


The research underscores the effectiveness of PRP monotherapy for skin rejuvenation, while also calling for the standardisation of PRP preparation protocols to ensure consistent results across future studies. The study's findings align with the growing body of evidence supporting PRP as a reliable and safe option for those seeking skin rejuvenation therapies.

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